Homo-VK-II-36
Homo-VK-II-36 is a carvedilol analog functioning as a selective inhibitor of the RyR2 channel, thereby suppressing store-overload-induced calcium release (SOICR) . This small molecule is utilized in cardiovascular research to investigate calcium signaling mechanisms in vitro and its role in conditions like catecholaminergic polymorphic ventricular tachycardia (CPVT) .
Product Specifications
CAS Number
1479049-35-8
Product Name Alternative
Homo-V-II-36, HomoVKII36, Homo-VK-II-36, Homo VK II 36, RyR2 channel
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
99.26% (May vary between batches)
Solubility
DMSO:4.61 mg/mL (10.01 mM)
Smiles
COc1ccccc1OCCN1CC (CCOc2cccc3[nH]c4ccccc4c23) OCC1=O
Molecular Formula
C27H28N2O5
Molecular Weight
460.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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