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YUM70

YUM70 is a potent and selective GRP78 inhibitor (IC50 = 1.5 μM) that induces ER stress and apoptosis in pancreatic cancer cells. It serves as a valuable chemical probe for studying ER stress mechanisms and apoptosis in both in vitro and in vivo cancer research models.

Product Specifications

CAS Number

423145-35-1

Product Name Alternative

Apoptosis, cancer, Heat shock proteins, Inhibitor, glucose-regulated, GRP78, HSP, endoplasmic, inhibit, pancreatic, stress-mediated, reticulum, protein, YUM 70, YUM70, YUM-70

Field of Research

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Purity

97.25% (May vary between batches)

Solubility

DMSO:100 mg/mL (250.73 mM)

Smiles

CCCC (=O) NC (c1ccc2OCOc2c1) c1cc (Cl) c2cccnc2c1O

Molecular Formula

C21H19ClN2O4

Molecular Weight

398.84

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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