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FHD-286

FHD-286 is a potent and selective ATPase inhibitor of the SWI/SNF chromatin remodeling complex subunits BRM (SMARCA2) and BRG1 (SMARCA4) . It serves as a valuable chemical probe for investigating BAF complex dysfunction in diseases, supporting both in vitro mechanistic studies and in vivo research in models of acute myeloid leukemia.

Product Specifications

CAS Number

2671128-05-3

Product Name Alternative

Inhibit, Inhibitor, FHD 286, FHD286, FHD-286, Epigenetic Reader Domain, EpigeneticReaderDomain, BRM/BRG1

Field of Research

Cell Biology, Epigenetics & Chromatin

Purity

98.70% (May vary between batches)

Solubility

DMSO:245 mg/mL (435.43 mM)

Smiles

COC[C@H] (NC (=O) c1ccn (c1) S (C) (=O) =O) C (=O) Nc1nc (cs1) -c1cccc (n1) N1C[C@H] (C) O[C@H] (C) C1

Molecular Formula

C24H30N6O6S2

Molecular Weight

562.66

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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