TNIK-IN-5
TNIK-IN-5 is a potent and selective TNIK inhibitor with an IC50 of 0.05 μM, effectively suppressing Wnt signaling in cellular assays. It demonstrates significant anti-proliferative activity against colorectal cancer cells in vitro, making it a valuable chemical probe for studying Wnt-driven oncogenesis and CRC-related research.
Product Specifications
CAS Number
2754265-66-0
Product Name Alternative
βcatenin, Wnt, Wnt pathway, Wnt/b-catenin, Wnt/betacatenin, Wnt/β-catenin, TNIK-IN-5, TNIKIN5, TNIK IN 5, TNIK, inhibit, Migration, Inhibitor, HCT116?cells, Cell proliferation, beta-catenin, betacatenin, Colorectal cancer, bcatenin
Field of Research
Neuroscience, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.58% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:1 mg/mL (2.69 mM) ; DMSO:10 mg/mL (26.93 mM)
Smiles
C (N1C=2C (=CC (=CC2) C=3C=C4C (=NC3) NC=C4) OC1=O) C5=CC (OC) =CC=C5
Molecular Formula
C22H17N3O3
Molecular Weight
371.39
Storage Conditions
-20°C
Notes
For research use only.
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