NI-57
NI-57 is a potent small molecule inhibitor targeting the BRPF family of proteins, exhibiting IC50 values of 3.1 nM for BRPF1, 46 nM for BRPF2/BRD1, and 140 nM for BRPF3. This compound is a valuable chemical probe for epigenetic research, enabling the investigation of BRPF function in chromatin regulation and gene expression in both cellular and biochemical assays.
Product Specifications
CAS Number
1883548-89-7
Product Name Alternative
BRPF1, BRPF2, BRPF3, inhibit, Inhibitor, NI 57, NI57, NI-57, EpigeneticReaderDomain, Epigenetic Reader Domain
Field of Research
Epigenetics & Chromatin
Purity
98.00% (May vary between batches)
Solubility
DMSO:80 mg/mL (208.65 mM) ;10% DMSO+90% Corn Oil:3.3 mg/mL (8.61 mM)
Smiles
COc1cc (ccc1S (=O) (=O) Nc1ccc2n (C) c (=O) c (C) cc2c1) C#N
Molecular Formula
C19H17N3O4S
Molecular Weight
383.42
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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