XL177A
XL177A is a potent and selective irreversible inhibitor of USP7 with an IC50 of 0.34 nM. Its anti-cancer activity is mediated through p53-dependent apoptosis, making it a valuable chemical probe for studying ubiquitination pathways in oncology research, both in vitro and in vivo.
Product Specifications
CAS Number
2417089-74-6
Product Name Alternative
DUBs, Deubiquitinase, cancer, inhibit, p53, Inhibitor, MCF7, XL177A, XL-177A, USP7
Field of Research
Cell Biology, Molecular Biology, Protein Biochemistry
Purity
98.75% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.32 mM) ; DMSO:55 mg/mL (63.84 mM)
Smiles
CN1CCN (CCC (=O) Nc2ccc3c (c2) ncn (CC2 (O) CCN (CC2) C (=O) [C@@H] (CCCNC (=O) c2ccc4c (Cl) c5CCCCc5nc4c2) Cc2ccccc2) c3=O) CC1
Molecular Formula
C48H57ClN8O5
Molecular Weight
861.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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