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RO-0335

RO-0335 is a potent diphenylether NNRTI with sub-nanomolar activity against wild-type HIV-1 (IC50 = 1.1 nM) . It demonstrates broad efficacy, maintaining activity (IC50 < 100 nM) against 92% of NNRTI-resistant clinical isolates in virological assays, supporting its use in antiretroviral resistance research.

Product Specifications

CAS Number

867365-76-2

Product Name Alternative

Inhibitor, HIV-1, inhibit, novel, nonnucleoside, diphenylether, potent, RO 0335, RO0335, RO-0335, Ro-0335, ReverseTranscriptase, Reverse Transcriptase

Field of Research

Infectious Disease & Virology

Purity

98.90% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.72 mM) ; DMSO:200 mg/mL (348.91 mM)

Smiles

NS (=O) (=O) c1ccc (NC (=O) Cc2ccc (Br) c (Oc3cc (Cl) cc (c3) C#N) c2F) c (Cl) c1

Molecular Formula

C21H13BrCl2FN3O4S

Molecular Weight

573.22

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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