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RET V804M-IN-1

RET V804M-IN-1 is a selective kinase inhibitor targeting wild-type RET with an IC50 of 20 nM, while also potently inhibiting the RET (V804M) gatekeeper mutant. This compound is a valuable chemical probe for investigating RET-driven oncogenesis in both cellular and biochemical assays.

Product Specifications

CAS Number

2414909-94-5

Product Name Alternative

RETV804M, RETV804M kinase inhibitor, RET V804M IN 1, RET V804MIN1, RET V-804M-IN-1, RET V804M-IN-1, RET, cRET, Inhibitor, inhibit, LUN 09945, LUN09945, LUN-09945

Field of Research

Cell Biology, Signal Transduction

Purity

96.97% (May vary between batches)

Solubility

DMSO:120 mg/mL (348.46 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (11.62 mM)

Smiles

NC (=O) c1ccc (cc1) -c1cnn2ccc (NCc3cccnc3) nc12

Molecular Formula

C19H16N6O

Molecular Weight

344.37

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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