Mogrol
Mogrol, the bioactive aglycone of mogrosides, acts as a signaling modulator by suppressing ERK1/2 and STAT3 pathways while activating AMPK, which concurrently reduces CREB activity. This mechanism supports its research utility in metabolic and inflammation studies, applicable in both cellular and animal models.
Product Specifications
CAS Number
88930-15-8
Product Name Alternative
Extracellular signal regulated kinases, ERK2, ERK, ERK1, Inhibitor, Mogrol, inhibit, STAT, STAT3
Field of Research
Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.21% (May vary between batches)
Solubility
DMSO:110 mg/mL (230.74 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.39 mM)
Smiles
[H][C@@]12CC[C@H] (O) C (C) (C) C1=CC[C@@]1 ([H]) [C@]3 (C) CC[C@H] ([C@H] (C) CC[C@@H] (O) C (C) (C) O) [C@@]3 (C) C[C@@H] (O) [C@@]21C
Molecular Formula
C30H52O4
Molecular Weight
476.73
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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