2-tert-Butyl-1,4-benzoquinone
2-tert-Butyl-1,4-benzoquinone (TBQ) is an electrophilic metabolite of BHA known to activate the Nrf2 pathway via S-arylation of Keap1 in RAW264.7 cells. This mechanism makes it a valuable tool for studying oxidative stress response, Nrf2 signaling, and cytoprotective gene regulation in both cellular and biochemical research models.
Product Specifications
CAS Number
3602-55-9
Product Name Alternative
2tertButyl1,4benzoquinone, 2-tert-Butyl-1,4-benzoquinone, 2 tert Butyl 1,4 benzoquinone, Nrf2
Field of Research
Cell Biology, Immunology & Inflammation, Signal Transduction
Purity
97.19% (May vary between batches)
Solubility
DMSO:60 mg/mL (365.41 mM)
Smiles
CC (C) (C) C1=CC (=O) C=CC1=O
Molecular Formula
C10H12O2
Molecular Weight
164.2
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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