GSK343
GSK343 is a potent and selective EZH2 inhibitor with IC50 of 4 nM, showing 60 fold selectivity against EZH1, and >1000 fold selectivity against other histone methyltransferases.
Product Specifications
CAS Number
1346704-33-3
Product Name Alternative
GSK343 | GSK-343 | GSK 343
Purity
>98% (HPLC)
Solubility
Ethanol: 4 mg/mL (7.38 mM) ; DMSO: 1 mg/mL warmed (1.84 mM)
Smiles
O=C (C1=CC (C2=CC (N3CCN (C) CC3) =NC=C2) =CC4=C1C=NN4C (C) C) NCC5=C (CCC) C=C (C) NC5=O
Molecular Formula
C31H39N7O2
Molecular Weight
541.69
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1-isopropyl-N- ((6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl) methyl) -6- (2- (4-methylpiperazin-1-yl) pyridin-4-yl) -1H-indazole-4-carboxamide.
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