Anticancer agent 274
Anticancer agent 274 (Compound 1) is a Sorafenib (HY-10201) analog. Anticancer agent 274 can inhibit the growth of tumor cells, with IC50 values of 0.034 μM and 0.042 μM against SaOS-2 and MNNG-HOS cells, respectively. Anticancer agent 274 has relatively low toxicity to normal cells and can be used in the research of tumors such as osteosarcoma[1].
Product Specifications
UNSPSC
12352005
Target
Drug Derivative
Related Pathways
Others
Field of Research
Cancer
Smiles
CC(NC1=CC=C(C=C1)OC2=CC=C(C=C2)NC(NC3=CC=CC=C3)=O)=O
Molecular Formula
C21H19N3O3
Molecular Weight
361.39
References & Citations
[1]Maria Dolors PUJOL DILMÉ, et al. Sorafenib analogs for use in the treatment of cancer. WO2025083280A1. 2025-04-24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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