BMS-309403
A potent, selective, cell-permeable and orally active inhibitor of FABP4 (Fatty acid binding protein 4) with Ki of < 2 nM; improves endothelial function, phosphorylated and total eNOS and reduces plasma triglyceride levels but does not affect endothelium-independent relaxations in mice; exhibits an effective therapeutic activity against severe atherosclerosis and type 2 diabetes in mouse models.
Product Specifications
CAS Number
300657-03-8
Product Name Alternative
BMS309403
Purity
>98% (HPLC)
Solubility
100 mM in DMSO
Smiles
CCc1c (c (nn1c2ccccc2c3cccc (c3) OCC (=O) O) c4ccccc4) c5ccccc5
Molecular Formula
C31H26N2O3
Molecular Weight
474.55
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2-[[2'- (5-ethyl-3,4-diphenyl-1H-pyrazol-1-yl) [1,1'-biphenyl]-3-yl]oxy]-acetic acid
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