AICAR
AICAR (Acadesine, AICA Riboside, NSC 105823) is a selective AMPK activator in both hepatocytes and adipocytes; inhibits the synthesis of fatty acids and sterols and inactivates HMG-CoA reductase in rat hepatocytes at 0.5 mM, inhibits insulin-stimulated glucose and reduces GLUT4 translocation in 3T3-L1 adipocytes; down-regulates the insulin receptor expression in HepG2 cells.
Product Specifications
CAS Number
2627-69-2
Product Name Alternative
Acadesine | AICA Riboside
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 30 mg/mL
Smiles
O=C (C1=C (N) N ([C@@H]2O[C@H] (CO) [C@@H] (O) [C@H]2O) C=N1) N
Molecular Formula
C9H14N4O5
Molecular Weight
258.2
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1H-Imidazole-4-carboxamide, 5-amino-1-β-D-ribofuranosyl-
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