STO-609
STO-609 is a selective and cell-permeable inhibitor of CaM-KK; inhibits recombinant CaM-KKα and CaM-KKβ with Ki of 80 and 15 ng/ml; without any significant effect on the downstream CaM kinases (CaM-KI and -IV, IC50 >10 ug) ; suppresses the Ca (2+) -induced activation of CaM-KIV in a dose-dependent manner in transfected HeLa cells; significantly reduces the endogenous activity of CaM-KK in SH-SY5Y neuroblastoma cells (1 ug/ml, 80% inhibition) .
Product Specifications
CAS Number
52029-86-4
Product Name Alternative
STO609 | ST O609
Field of Research
Epigenetics & Chromatin
Purity
>98% (HPLC)
Solubility
DMSO: 5.6 mg/mL (Need ultrasonic and warming)
Smiles
C1=CC=C2C (=C1) N=C3N2C (=O) C4=CC=CC5=C (C=CC3=C54) C (=O) O
Molecular Formula
C19H10N2O3
Molecular Weight
314.2943
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
7H-Benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid, 7-oxo-
Available Sizes
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