KC7F2
A small molecule HIF-1α translation inhibitor with IC50 of 20 uM; prevents the activation of HIF-target genes such as CA IX, MMP2, Endothelin 1, and Enolase 1; down regulates of HIF-1α protein synthesis by suppression of the phosphorylation of 4EBP1 and p70S6K.
Product Specifications
CAS Number
927822-86-4
Product Name Alternative
KC7F2
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 32 mg/mL
Smiles
ClC1=C (S (NCCSSCCNS (C2=C (Cl) C=CC (Cl) =C2) (=O) =O) (=O) =O) C=C (Cl) C=C1
Molecular Formula
C16H16Cl4N2O4S4
Molecular Weight
570.3812
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Benzenesulfonamide, N, N'- (dithiodi-2,1-ethanediyl) bis[2,5-dichloro-
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