BDNF antibody
Product Specifications
Background
During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation(LTP), long-term depression(LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
Synonyms
Brain-derived neurotrophic factor (BDNF)|Abrineurin|BDNF precursor form (ProBDNF)|BDNF
Host
Mouse
Reactivity
Human
Immunogen
brain-derived neurotrophic factor
Target
BDNF
Clonality
Monoclonal
Isotype
IgG2a
Applications
ELISA, WB
Purification
Protein A+G purification
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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