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BDNF antibody

Product Specifications

Background

During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation(LTP), long-term depression(LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.

Synonyms

Brain-derived neurotrophic factor (BDNF)|Abrineurin|BDNF precursor form (ProBDNF)|BDNF

Host

Mouse

Reactivity

Human

Immunogen

brain-derived neurotrophic factor

Target

BDNF

Clonality

Monoclonal

Isotype

IgG2a

Applications

ELISA, WB

Purification

Protein A+G purification

Dilution

WB: 1:500-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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