ISCK03
A specific c-Kit inhibitor that inhibits c-kit phosphorylation in vitro and SCF-induced c-kit phosphorylation in human melanoma cells; also inhibits p44/42 ERK mitogen-activated protein kinase (MAPK) phosphorylation, does not inhibit HGF-induced phosphorylation of p44/42 ERK proteins; induces the dose-dependent depigmentation of newly regrown hair, promotes the depigmentation of UV-induced hyperpigmented spots in vivo; orally acitve.
Product Specifications
CAS Number
945526-43-2
Product Name Alternative
ISCK 03 | ISCK-03
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 38 mg/mL
Smiles
O=S (N (C1=CC=C (C (C) (C) C) C=C1) C2=CC=C (N3C=CN=C3) C=C2) =O
Molecular Formula
C19H21N3O2S
Molecular Weight
355.45394
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Benzenesulfonamide, 4- (1,1-dimethylethyl) -N-[4- (1H-imidazol-1-yl) phenyl]-
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