HDAC8-IN-1
MDK-7933 (HDAC8-IN-1) is a potent and selective HDAC8 inhibitor (IC50 = 27.2 nM) . It demonstrates antiproliferative and cytotoxic activity against human lung cancer cell lines, including A549, H1299, and CL1-5, while showing minimal effects on normal IMR-90 cells. This compound is a valuable research tool for studying HDAC8 biology in oncology and cancer cell signaling pathways.
Product Specifications
CAS Number
1417997-93-3
Product Name Alternative
HDAC8, HDAC8 IN 1, HDAC8IN1, HDAC-8-IN-1, HDAC8-IN-1, HDAC, Inhibitor, Histone deacetylases, inhibit
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
97.13% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.79 mM) ; DMSO:55 mg/mL (159.24 mM)
Smiles
COc1ccc (\C=C\C (=O) NO) c (c1) -c1ccc (cc1) -c1ccccc1
Molecular Formula
C22H19NO3
Molecular Weight
345.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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