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TDZD-8

A potent, selective, non-ATP competitive GSK-3β inhibitor with IC50 of 2 uM; displays no activity against PKA, CK-2, PKC, and CDK1 (IC50>100 uM) ; reduces the colonic inflammation induced by TNBS in vivo, also prevents 6-OHDA-induced neuronal cell death.

Product Specifications

CAS Number

327036-89-5

Product Name Alternative

TDZD 8 | TDZD8 | GSK-3β Inhibitor I | NP 01139

Purity

>98% (HPLC)

Solubility

10 mM in DMSO

Smiles

O=C (N1CC2=CC=CC=C2) N (C) SC1=O

Molecular Formula

C10H10N2O2S

Molecular Weight

222.2636

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

1,2,4-Thiadiazolidine-3,5-dione, 2-methyl-4- (phenylmethyl) -

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