Anti-SIRT1

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]

Product Specifications

CAS Number

9007-83-4

Reactivity

Human

Immunogen

Rabbit polyclonal SIRT1 antibody was raised against a peptide from the C terminal residues of human SIRT1 protein.

Clonality

Polyclonal

Type

Antibodies-Polyclonal

Applications

WB,ELISA

Concentration

100ug/100ul

Purity

Affinity purified

Buffer

PBS, pH 7.4 with 0.02% Sodium Azide

Shipping Conditions

Ice Pack

Storage Conditions

This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Fragment

IgG

Applications Notes

For research use only Peptide ELISA titer: 1:5000-1:20000 Western blot analysis: 1:200-1:1,000 Optimal dilutions/concentrations should be determined by the end use.