E6446 dihydrochloride
E6446 dihydrochloride is a novel synthetic antagonist for nucleic acid-sensing TLRs; potently suppressed DNA stimulation of HEK:TLR9 cells with IC50 of 10 nM.
Product Specifications
CAS Number
1345675-25-3
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 7.6 mg/mL (14.55 mM)
Smiles
C1 (c2ccc (OCCCN3CCCC3) cc2) nc2ccc (OCCCN3CCCC3) cc2o1.Cl.Cl
Molecular Formula
C27H37Cl2N3O3
Molecular Weight
522.51
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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