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SC-560

SC-560 is a potent, orally active and selective inhibitor of COX-1. Using human recombinant enzymes, the IC50 value for SC-560 with respect to COX-1 is 9 nM, while the corresponding IC50 value for COX-2 is 6.3 μM.1 Thus, SC-560 shows 700-fold selectivity for the COX-1 enzyme.

Product Specifications

CAS Number

188817-13-2

Product Name Alternative

SC-560 | SC 560 | SC560

Purity

>98% (HPLC)

Solubility

DMSO : ≥ 100 mg/mL 283.49 mM; H2O : < 0.1 mg/mL

Smiles

COc1ccc (cc1) n1c (cc (n1) C (F) (F) F) c1ccc (cc1) Cl

Molecular Formula

C17H12ClF3N2O

Molecular Weight

352.74

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

5- (4-chlorophenyl) -1- (4-methoxyphenyl) -3- (trifluoromethyl) -1H-pyrazole

Available Sizes

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