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Bivalirudin

Bivalirudin is a reversible inhibitor of α- and ζ-thrombin (Kis = 2.56 and 1.84 nM respectively) enzymes that exhibit high fibrinogen-clotting activities. (In Vivo) :Bivalirudin (2 mg/kg) delays both the time for appearance of first thrombus and the time for occlusion in P2Y12+/+ arteries, although neither prevented vessel occlusion.

Product Specifications

CAS Number

128270-60-0

Product Name Alternative

Hirulog-1 | BG-8967

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

In Vitro: H2O : 10 mg/mL (4.59 mM)

Smiles

CC[C@H] (C) [C@H] (NC (=O) [C@H] (CCC (O) =O) NC (=O) [C@H] (CCC (O) =O) NC (=O) [C@H] (Cc1ccccc1) NC (=O) [C@H] (CC (O) =O) NC (=O) CNC (=O) [C@H] (CC (N) =O) NC (=O) CNC (=O) CNC (=O) CNC (=O) CNC (=O) [C@@H]1CCCN1C (=O) [C@H] (CCCNC (N) =N) NC (=O) [C@@H]1CCCN1C (=O) [C@H] (N) Cc1ccccc1) C (=O) N1CCC[C@H]1C (=O) N[C@@H] (CCC (O) =O) C (=O) N[C@@H] (CCC (O) =O) C (=O) N[C@@H] (Cc1ccc (O) cc1) C (=O) N[C@@H] (CC (C) C) C (O) =O

Molecular Formula

C98H138N24O33

Molecular Weight

2180.29

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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