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Pico145

Pico145 is a remarkable inhibitor of TRPC1/4/5 channels. Pico145 inhibits () -englerin A-activated TRPC4/TRPC5 channels (IC50s: 0.349 and 1.3 nM in cells) It also shows no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, TRPM8.

Product Specifications

CAS Number

1628287-16-0

Product Name Alternative

HC-608

Purity

>98% (HPLC)

Solubility

DMSO : 99 mg/mL (188.61 mM)

Smiles

CN (c1c (C (N2CCCO) =O) n (Cc (cc3) ccc3Cl) c (Oc3cc (OC (F) (F) F) ccc3) n1) C2=O

Molecular Formula

C23H20ClF3N4O5

Molecular Weight

524.88

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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