DNA2 inhibitor C5
DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM) . DNA2 inhibitor C5 inhibits nuclease, DNA dependent ATPase, helicase, and DNA binding activities of DNA2.
Product Specifications
CAS Number
35973-25-2
Field of Research
Epigenetics & Chromatin; Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO:31.25 mg/mL (133.45 mM; Need ultrasonic)
Smiles
O=C (C1=C (O) C2=CC=CC ([N+] ([O-]) =O) =C2N=C1) O
Molecular Formula
C10H6N2O5
Molecular Weight
234.17
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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