Human IL-1RA Protein, Tag Free (MALS verified)
Interleukin-1 receptor antagonist (IL-1RA) is a naturally occurring anti-inflammatory antagonist of interleukin-1 family of pro-inflammatory cytokines. It competes with IL-1α and IL-1β to bind IL-1R1, thereby acting as an endogenous inhibitor of the IL-1 signaling pathway. IL‐1RA has been connected with a variety of diseases, including cardiovascular disease, type II diabetes, carcinoma, and joint diseases.
Product Specifications
Expression Region
Arg 26 - Glu 177
Reactivity
Human
Conjugation
Unconjugated
Tag
Native
Field of Research
Immunology & Inflammation
Endotoxin
1.0 EU per μg
Purity
95%
Form
Powder
Molecular Weight
17.3 kDa
Storage Conditions
-20°C
Notes
For research use only.
Applications Notes
This protein carries no "tag". The protein has a calculated MW of 17.3 kDa. The protein migrates as 15-16 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) .
NCBI Accession Number
P18510
Preservative
PBS, pH 7.4
Available Sizes
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