MCP-4 (CCL13)
The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross- reacts across species. Recombinant murine MCP-2 is an 8.6 kDa protein containing 75 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
Product Specifications
Synonyms
CCL13; NCC1; CKb10; MCP-4; NCC-1; SCYL1; SCYA13
NCBI Gene ID
6357
UniProt
Q99616
Accession Number
NP_005399
Accession Number mRNA
NM_005408
Chromosomal Location
17q11.2
Reactivity
Human
Cross Reactivity
Monkey, Mouse, Human, Leech
Sequence
QPDALNVPST CCFTFSSKKI SLQRLKSYVI TTSRCPQKAV IFRTKLGKEI CADPKEKWVQ NYMKHLGRKA HTLKT
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to chemoattract human monocytes using a concentration of 10.0-100.0 ng/ml.
Length
75
Form
Lyophilized
Molecular Weight
8.6 kDa
Host or Source
E. coli
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