Protoapigenone
Protoapigenone is an antineoplastic agent isolated from ferns. Protoapigenone has significant inhibitory activity against Hep G2, Hep 3B, MCF-7, A549 and MDAMB-231, with IC50s values of 1.60, 0.23, 0.78, 3.88 and 0.27 μg/mL respectively[1].
Product Specifications
CAS Number
[862884-32-0]
UNSPSC
12352005
Hazard Statement
H317
Target
Apoptosis; Bcl-2 Family; Caspase
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protoapigenone.html
Purity
99.84
Solubility
10 mM in DMSO
Smiles
OC1=C2C(OC(C3(O)C=CC(C=C3)=O)=CC2=O)=CC(O)=C1
Molecular Formula
C15H10O6
Molecular Weight
286.24
Precautions
H317
References & Citations
[1]Lin A S, et al. New cytotoxic flavonoids from Thelypteris torresiana[J]. Planta medica, 2005, 71 (09) : 867-870.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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