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Recombinant Human HER3 Protein

Recombinant Human Receptor Tyrosine-Protein Kinase ErbB-3 is produced by our Mammalian expression system and the target gene encoding Ser20-Thr643 is expressed with a human IgG1 Fc tag at the C-terminus.

Product Specifications

Product Name Alternative

Proto-oncogene-like protein c-ErbB-3; Tyrosine kinase-type cell surface receptor HER3; ERBB3; HER3

UniProt

P21860

Expression Region

Ser20-Thr643

Conjugation

Unconjugated

Tag

C-Fc

Origin

Human

Field of Research

Signal Transduction

Endotoxin

< 1 EU/μg as determined by LAL test.

Purity

SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.

Bioactivity

BLI: Loaded Human NRG1Beta (245AA) (Cat#orb3002365) on APS Biosensor, can bind Human HER3-Fc (Cat#orb2993758) with an affinity constant of 2.1 nM as determined in BLI assay.

Form

Lyophilized

Molecular Weight

Predicted: 95.6 KDa. Observed: 120-140 KDa, reducing conditions

Storage Conditions

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Notes

For research use only.

Preservative

0.2 μm filtered solution of 20 mM Tris-HCl, 10% Trehalose, 2% Mannitol, 0.05% Tween 80, pH 9.0.

Available Sizes

Frequently Asked Questions

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