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HIV-1 inhibitor-64

Product Specifications

UNSPSC Description

HIV-1 inhibitor-64 (Compound 7c) is a wild-type HIV-1 inhibitor that effectively suppresses the activity of HIV-1 mutants E138K/Q148K and G140S/Q148R with EC50 values of 62.5 nM and 11.3 nM, respectively. HIV-1 inhibitor-64 exhibits antiviral activity and can be used in the research of AIDS[1].

Target Antigen

HIV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/hiv-1-inhibitor-64.html

Solubility

10 mM in DMSO

Smiles

O=C(N(C(C)C)CCN1C=C2C(NCC3=C(F)C=C(F)C=C3)=O)C1=C(O)C2=O

Molecular Weight

391.37

References & Citations

[1]Mahajan, et al. "N-Substituted Bicyclic Carbamoyl Pyridones: Integrase Strand Transfer Inhibitors that Potently Inhibit Drug-Resistant HIV-1 Integrase Mutants." ACS Infectious Diseases (2024).

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-162253/HIV-1-inhibitor-64-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-162253/

Clinical Information

No Development Reported

CAS Number

2919019-36-4

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