Biotin-epoxomicin
Biotin-epoxomicin is a biotin labeled Epoxomicin (HY-13821) . Biotin-epoxomicin is a high affinity probe targeting Proteasome. Biotin-epoxomicin covalently binds to multiple proteasome catalytic subunits (such as LMP7, Z and MECL1) [1].
Product Specifications
CAS Number
[1334608-28-4]
UNSPSC
12352209
Target
Proteasome
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Smiles
O=C([C@]1(CO1)C)[C@H](CC(C)C)NC([C@H]([C@H](O)C)NC([C@H]([C@@H](C)CC)NC([C@H]([C@@H](C)CC)NC(CCCC[C@H]2[C@]3([H])[C@](NC(N3)=O)([H])CS2)=O)=O)=O)=O
Molecular Formula
C35H60N6O8S
Molecular Weight
724.95
References & Citations
[1]Sin N, et al. Total synthesis of the potent proteasome inhibitor epoxomicin: a useful tool for understanding proteasome biology. Bioorg Med Chem Lett. 1999 Aug 2;9 (15) :2283-8.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
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