Pavinetant
Product Specifications
UNSPSC Description
Pavinetant (MLE-4901) is a neurokinin-3 receptor (NK3R) antagonist.
Target Antigen
Neurokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/MLE-4901.html
Solubility
DMSO : ≥ 50 mg/mL
Smiles
CC[C@H](NC(C1=C(C=CC=C2)C2=NC(C3=CC=CC=C3)=C1NS(C)(=O)=O)=O)C4=CC=CC=C4
Molecular Weight
459.56
References & Citations
[1]Li Y, et al. In vitro assessment of metabolic drug–drug interaction potential of AZD2624, neurokinin-3 receptor antagonist, through cytochrome P(450) enzyme identification, inhibition, and induction studies. Xenobiotica. 2010 Nov;40(11):721-9.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-14432/Pavinetant-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-14432/Pavinetant-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
941690-55-7
Available Sizes
Curated Selection
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