(R) -VX-11e

(R) -VX-11e (Compound 1) is an ERK2 inhibitor[1].

Product Specifications

CAS Number

[1680187-43-2]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

ERK

Type

Reference compound

Related Pathways

MAPK/ERK Pathway; Stem Cell/Wnt

Applications

Cancer-Kinase/protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/r-vx-11e.html

Purity

98.73

Solubility

DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=CC(C2=NC(NC3=C(Cl)C=C(F)C=C3)=NC=C2C)=CN1)N[C@@H](CO)C4=CC=CC(Cl)=C4

Molecular Formula

C24H20Cl2FN5O2

Molecular Weight

500.35

Precautions

H302, H315, H319, H335

References & Citations

[1]Vanderpool D, et al. Residence time and kinetic efficiency analysis of extracellular signal-regulated kinase 2 inhibitors. Anal Biochem. 2015 Mar 15;473:46-52.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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