Recombinant Human FGF basic Protein (Trx Tag)
Product Specifications
Background
Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in remodeling damaged tissue, such as ulcer healing, vascular repair, traumatic brain injury (TBI) . bFGF is a critical component of human embryonic stem cell culture medium. In addition, bFGF protein is a heparin-binding cationic protein involved in a variety of pathological conditions including angiogenesis and solid tumour growth. Thus, bFGF is regarded as a target for cancers chemopreventive and therapeutic strategies.
Abbreviation
FGF basic
Synonyms
HBGF; FGF; BFGF; FGF-2; FGFB; HBGF-2; Basic FGF; FGF2; Basic Fibroblast Growth Factor; B-FGF; FGF-β; Fibroblast Growth Factor 2; heparin-binding growth factor 2; prostatropin; BFGF; B-FGF; FGF-2; FGFB; fibroblast growth factor 2; HBGF-2; heparin-binding growth factor 2; prostatropin; basic; Basic fibroblast growth factor bFGF; FGF 2; FGF B; FGF2 basic; Fibroblast growth factor; Fibroblast growth factor 2 (basic) ; HBGF 2; HBGF2; HBGH 2; HBGH2; Heparin binding growth factor 2 precursor; heparin-binding growth factor 2; FGF-β
UniProt
P09038
Accession Number
P09038
Expression System
E.coli
Tag
N-Trx
Sequence
Pro143-Ser288
Field of Research
Cardiovascular; Signal Transduction; Neuroscience; Stem Cells; Cancer; Developmental Biology
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
36.1 kDa
Observed Molecular Weight
33 kDa
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Species
Human
Available Sizes
Curated Selection
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