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TFE3 Polyclonal Antibody

This is a TFE3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants.

Synonyms

TFE3, RCCP2, RCCX1, TFEA, bHLHe33

Gene ID

7030

Swiss Prot

P19532

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human TFE3

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.02% sodium azide,50% glycerol, pH7.3.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

95kDa

Observed Molecular Weight

120kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Frequently Asked Questions

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