ERO1LB Polyclonal Antibody
This is a ERO1LB Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Other protein disulfide isomerase family members can also be reoxidized, but at lower rates compared to P4HB, including PDIA2 (50% of P4HB reoxidation rate, as well as PDIA3, PDIA4, PDIA6 and NXNDC12 (<10%. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS in the cell. May be involved in oxidative proinsulin folding in pancreatic cells, hence may play a role in glucose homeostasis.
Synonyms
ERO1B, ERO1LB, Ero1beta
Gene ID
56605
Swiss Prot
Q86YB8
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human ERO1LB
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
167kDa/202kDa/227kDa/228kDa/232kDa
Observed Molecular Weight
245kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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