DnaseIPolyclonal Antibody
This is a DnaseI Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Deoxyribonuclease I (DNase I) is an endonuclease which is secreted to cleave DNA in the extracellular space down to an average of tetranucleotides with 5′ monophosphate and 3′ hydroxyl DNA ends . Both single-stranded DNA and double-stranded DNA are degraded by Dnase I. This nuclease appears to account for the major nucleolytic activity on DNA in serum and is responsible for the degradation of the majority of circulating DNA derived from apoptotic and necrotic cell death and from neutrophil extracellular traps. In addition to its role in the serum, it has been proposed as one of the deoxyribonucleases responsible for DNA fragmentation in the process of apoptosis.
Synonyms
Deoxyribonuclease-1, DNASE1, DNL1, DRNI
Gene ID
1773
Swiss Prot
P24855
Reactivity
Human
Immunogen
Recombinant Human DnaseI protein expressed by E.coli.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.7mg/mL
Dilution
WB 1:1000-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
15kDa
Observed Molecular Weight
23kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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