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HMGA1 Polyclonal Antibody

This is a HMGA1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene.

Synonyms

High mobility group (nonhistone chromosomal) protein isoforms I and Y, High mobility group AT hook 1, High mobility group AT-hook protein 1, High mobility group protein 1, High mobility group protein A1, High mobility group protein HMG-I/HMG-Y, High mobility gr

Swiss Prot

P17096

Accession Number

NP_665906

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide of human HMGA1

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IHC, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

0.6 mg/mL

Dilution

IHC 1:50-200, ELISA 1:2000-10000

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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