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LZTFL1 Polyclonal Antibody

This is a LZTFL1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in this gene cause a form of Bardet-Biedl Syndrome; a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. This gene may also function as a tumor suppressor; possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. Alternative splicing of this gene results in multiple transcript variants.

Synonyms

5530402H04Rik,6130400H19Rik, AI414725, AW048545, BBS17, DKFZp686H2076, FLJ36386, Leucine zipper transcription factor like 1, Leucine zipper transcription factor like protein 1, Leucine zipper transcription factor-like protein 1, LZTFL 1, Lztfl1, Lztfl1 leucine zippe

Swiss Prot

Q9NQ48

Accession Number

BC025988

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human LZTFL1

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

0.3 mg/mL

Dilution

WB 1:500-1:2000, IHC 1:25-1:100

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

35 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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