Calponin Rabbit monoclonal antibody

Product Specifications

Background

Calponin regulates smooth muscle cell contraction and is a marker of smooth muscle cell differentiation. Calponin, an Actin- and Tropomyosin-binding protein, is characterized as an inhibitory factor of smooth-muscle actomyosin activity. Calponin is implicated in the regulation of smooth muscle contraction through its interaction with F-Actin and inhibition of the Actin-activated MgATPase activity of phosphorylated Myosin.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

Calponin-1; Basic calponin; Calponin H1, smooth muscle; CNN1

Swiss Prot

P51911

Reactivity

Human Mouse Rat Dog Pig

Immunogen

A synthesized peptide derived from human Calponin

Conjugation

Unconjugated

Applications

WB IHC ICC/IF

Dilution

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

Purity

Affinity-chromatography

Modification

Unmodified

Molecular Weight

~ 33 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Calponin Antibody detects endogenous levels of total Calponin

Applications Notes

Western blot (WB) analysis of Calponin Rabbit monoclonal antibody at 1:500 dilution Lane1:The stomach tissue lysate of Mouse (30ug) Lane2:K562 whole cell lysate (30ug)