PIM1 Polyclonal Antibody
This is a PIM1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons.
Synonyms
Oncogene PIM 1, Oncogene PIM1, PIM 1, pim 1 kinase 44 kDa isoform, Pim 1 kinase, pim 1 oncogene (proviral integration site 1), Pim 1 oncogene, PIM, PIM1, pim1 kinase 44 kDa isoform, PIM1, Pim2, PIM3, Proto oncogene serine/threonine protein kinase Pim 1, Proto-oncogene
Swiss Prot
P11309
Accession Number
BC020224
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human PIM1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.3 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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