JAK1-IN-16
Product Specifications
UNSPSC Description
JAK1-IN-16 (compound 4l) is an inhibitor of JAK1/STAT3 and effectively downregulates TLR4 protein expression.[1].
Target Antigen
JAK; STAT; Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Epigenetics;Immunology/Inflammation;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/jak1-in-16.html
Smiles
CC1=CC=C(C=C1)C2=NN=C(C=C2)SCC(NC3=CC=C(C(C(F)(F)F)=C3)Cl)=O
Molecular Weight
437.87
References & Citations
[1]Shaldam MA, et al. Muti-target rationale design of novel substituted N-phenyl-2-((6-phenylpyridazin-3-yl)thio)acetamide candidates as telomerase/JAK1/STAT3/TLR4 inhibitors: In vitro and in vivo investigations. Bioorg Chem. 2024 Dec;153:107843.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-169242/JAK1-IN-16-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-169242/
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
