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AMACR Polyclonal Antibody

This is a AMACR Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R) - and (S) -stereoisomers. The conversion to the (S) -stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.

Synonyms

2 methylacyl CoA racemase,2-methylacyl-CoA racemase, Alpha methylacyl CoA racemase, Alpha-methylacyl-CoA racemase, Amacr, AMACR, AMACRD, CBAS4, EC 5.1.99.4, Macr1, RACE, RM

Swiss Prot

Q9UHK6

Accession Number

BC009471

Reactivity

Human

Immunogen

Recombinant protein of human AMACR

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

0.1 mg/mL

Dilution

WB 1:500-1:2000, IHC 1:25-1:100

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

42 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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