TGF β Receptor I Polyclonal Antibody

The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS) . Multiple transcript variants encoding different isoforms have been found for this gene.

AAT 5, AAT5, Activin A receptor type II like kinase 53kDa, Activin A receptor type II like kinase,53kD, Activin A receptor type II like protein kinase of 53kD, activin A receptor type II-like kinase,53kDa, activin A receptor type II-like protein kinase of 53kD