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Anti-pro Caspase 9 CASP9 Rabbit Monoclonal Antibody, Carrier-free

Selected Variant

M00080-1-carrier-free

Size: 100 µL

Boster Bio Anti-pro Caspase 9 CASP9 Rabbit Monoclonal Antibody catalog # M00080-1. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human.

Product Specifications

Synonyms

Caspase-9;CASP-9;3.4.22.62;Apoptotic protease Mch-6;Apoptotic protease-activating factor 3;APAF-3;ICE-like apoptotic protease 6;ICE-LAP6;Caspase-9 subunit p35;Caspase-9 subunit p10;CASP9;MCH6;

Gene Name

Caspase-9

UniProt

P55211

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human pro Caspase 9

Clonality

Monoclonal

Clone

Clone: GAH-3

Tissue Specificity

Ubiquitous, with highest expression in the heart, moderate expression in liver, skeletal muscle, and pancreas. Low levels in all other tissues. Within the heart, specifically expressed in myocytes. .

Applications

WB,IHC,Flow Cytometry

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly (ADP- ribose) polymerase (PARP).

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

46281 MW

Observed Molecular Weight

46 kDa

Fragment

Rabbit IgG

Applications Notes

WB 1:500-1:2000<br>IHC 1:50-1:200<br>FC 1:50

Subcellular Location

Cytoplasm, cytosol. Nucleus. Cytosolic under unstressed conditions, translocates into the nucleus upon induction by electrophilic agents.

Protein Name

P2X purinoceptor 1

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