Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-PF4 Antibody Picoband® (FITC Conjugate)

Boster Bio Anti-PF4 Antibody Picoband® catalog # PB10012. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Platelet factor 4 (PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4). By in situ hybridization, the CXCL4 gene is mapped to chromosome 4q12-q21. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair.

Synonyms

Platelet factor 4;PF-4;C-X-C motif chemokine 4;Pf4;Cxcl4, Scyb4;

Gene Name

Platelet factor 4

UniProt

Q9Z126

Host

Rabbit

Reactivity

Mouse

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E. coli-derived mouse PF4 recombinant protein (Position: V30-S105). Mouse PF4 shares 74.3% and 86.8% amino acid (aa) sequence identity with human and rat PF4, respectively.

Clonality

Polyclonal

Tissue Specificity

Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus. .

Applications

ELISA,IHC,WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation (By similarity). .

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=PB10012

Product MSDS

https://www.bosterbio.com/msds?sku=PB10012

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.1-0.5μg/ml, Mouse<br> Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Mouse, By Heat<br> ELISA, 0.1-0.5μg/ml, -<br>

Subcellular Location

Secreted.

Sequence Similarities

Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC4 sub-subfamily.

Protein Name

Platelet factor 4

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Rabbit Polyclonal UNC5H1/Unc5a Antibody [CoraFluor 1]
NBP3-00125CL1 0.1 mL

Rabbit Polyclonal UNC5H1/Unc5a Antibody [CoraFluor 1]

Ask
View Details
Nopp140 siRNA (h)
sc-38127 10 µM

Nopp140 siRNA (h)

Ask
View Details
Mouse Monoclonal MYCL1/L-Myc Antibody (PCRP-MYCL-2D5)
NBP3-13977-100ug 100 µg

Mouse Monoclonal MYCL1/L-Myc Antibody (PCRP-MYCL-2D5)

Ask
View Details
Frozen Tissue Sections, Kidney
CS524982 5x 5 µm

Frozen Tissue Sections, Kidney

Ask
View Details