Arg-Gly-Asp-Ser

The RGDS peptide is a conserved integrin-binding motif found in extracellular matrix proteins like fibronectin. It serves as a potent inhibitor of platelet aggregation by blocking fibrinogen binding to integrin αIIbβ3, making it a key tool for studying thrombosis and cell adhesion in both in vitro and in vivo research models.