Olanexidine (hydrochloride)

Olanexidine hydrochloride is a monobiguanide compound with bactericidal activity. Olanexidine probably binds to the cell membrane, destroys membrane integrity. Olanexidine hydrochloride is active against a wide range of bacteria, including Gram-positive and Gram-negative bacteria. Olanexidine exhibits the bactericidal concentration of 109 μg/mL for Gram-positive bacilli[1].

Product Specifications

CAS Number

[146509-94-6]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/olanexidine-hydrochloride.html

Purity

96.25

Solubility

DMSO : 62.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

N=C(NC(NCCCCCCCC)=N)NCC1=CC=C(C(Cl)=C1)Cl.[H]Cl

Molecular Formula

C17H28Cl3N5

Molecular Weight

408.80

References & Citations

[1]Hagi A, et al. Bactericidal Effects and Mechanism of Action of Olanexidine Gluconate, a New Antiseptic. Antimicrob Agents Chemother. 2015 Aug;59 (8) :4551-9.