GLUT4 activator 2
GLUT4 activator 2 (C59) is an insulin sensitizer, which can be used for research of diabetic diseases. GLUT4 activator 2 improves glucose uptake and insulin sensitivity in rodents. GLUT4 activator 2 interacts with Unc119 and Unc119B resulting in increased insulin sensitivity and GLUT4 translocation[1].
Product Specifications
CAS Number
[2761446-81-3]
UNSPSC
12352005
Target
Insulin Receptor; Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/glut4-activator-2.html
Purity
99.92
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C1(C[C@@H](C2)C3)C[C@@H]3C[C@@H]2C1)NC(N=C4)=CC(Cl)=C4Cl
Molecular Formula
C16H18Cl2N2O
Molecular Weight
325.23
References & Citations
[1]Yin TC, et al. Insulin sensitization by small molecules enhancing GLUT4 translocation. Cell Chem Biol. 2023 Aug 17;30 (8) :933-942.e6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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